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Dr. Hussnain A Janjua
Assistant Professor
Industrial Biotechnology

ASAB
National University of Sciences and Technology (NUST)
Campus H-12, Islamabad
Tel : +92-51-9085-6149

Specialization
Microbes as biocatalysts and biofuel cells, genomics and proteomics of pathogenic and environmental microorganisms, metabolic engineering and synthetic microbiology for bioactive microbial metabolites, biosynthesis of silver nanoparticles         

Education
PhD (2005): ImperialCollage London, United Kingdom, Post Doctoral Research Fellow (2005-2007): IMBM, UWC, Cape Town, South Africa. Post Doctoral Research Fellow (2007-2011): CIBIO, UNITN, Italy

Dr Hussnain A Janjua earned his doctoral degree in Microbial Molecular Biology in 2005 from the Imperial College London under the supervision of Professor David Leak. His work was focused on Molecular Genetics of Xanthobacter autotrophicus Py2. After completing his PhD he was given a consultancy position in the same lab. Later in 2005, he was awarded Postdoctoral Research Fellowship and moved to “Institute for Microbial Biotechnology and Metagenomics” (IMBM) at the University of Western Cape in Cape Town, South Africa where he worked with Professor Don Cowan on Fungal solubilization of low rank coal into chemical commodities of industrial applications. In 2007 he managed to win research funding from Provincia Autonoma di Trento, Italy for a project titled ‘Genome Plasticity of P. aeruginosa: from comparative genomics to virulence’. He joined Laboratory of Microbial Genomics at the Centre for Integrative Biology (CIBIO), Universita Degli Studi Di Trento where he worked with Dr Olivier Jousson as a Post Doctoral Research Fellow till June 2011 on host-pathogen interactions, genotyping and comparative genomics of P. aeruginosa clinical isolates. In September 2011 Dr Janjua joined Quaid-i-Azam University as HEC Foreign Professor where he was among the founding faculty members of the Department of Pharmacy. Dr Janjua has also spent few months at Syed Babar Ali School of Science and Engineering (LUMS) where he was involved in developing Microbiology, Virology and Biochemistry courses he was also involved in research projects focused on the antimicrobial applications of different types of silver nanomaterials. Dr Janjua is currently employed at ASAB, NUST since september 2012, he is actively involved in industrial biotechnology research, he is supervising 4 MSc and 3 PhD students. He has also developed Industrial Biotechnology, Gene Therapy and Modern Research Techniques courses at post graduate and undergraduate level.
Major Research Projects

•     Synthesis of silver nano-particles using cellular extracts (1-MSc and 1-BSc Student)
•     Cyanobacteria and Microalgae for bioactive compounds synthesis (1-PhD Student)
•     HCV, comparative genomics and host pathogen interactions (2-PhD Student).
•     Isolation, identification and characterization of bacterial and fungal strains that grow on carboxymethyl cellulose (1 MSc Student)
 
Collaborative Insilico Research Projects

•    Modeling Simulation and verification of qualitative behaviours of the Biological Regulatory Networks
      (BRN) in HIV infection,
•    Modeling Simulation and verification of qualitative behaviours of the Biological Regulatory Networks
      (BRN) in tolerogenic Indolamine2, 3 diooxygenase in Tumor.
1.   Clinical populations of Pseudomonas aeruginosa isolated from acute infections show a wide virulence range partially correlated with population structure and virulence gene expression. Janjua HA, Segata N, Bernabò P, Tamburini S, Ellen A, Jousson O. Microbiology. 2012 Aug;158(Pt 8):2089-98. doi: 10.1099/mic.0.056689-0. Epub 2012 May 3.
 
 
2.   Mathematical modeling of bacterial virulence and host-pathogen interactions in the Dictyostelium/Pseudomonas system. Fumanelli L, Iannelli M, Janjua HA, Jousson O. J Theor Biol. 2011 Feb 7;270(1):19-24. doi: 10.1016/j.jtbi.2010.11.018. Epub 2010 Nov 13.
 
3.   Degradation of low rank coal by Trichoderma atroviride ES11. Silva-Stenico ME, Vengadajellum CJ, Janjua HA, Harrison ST, Burton SG, Cowan DA. J Ind Microbiol Biotechnol. 2007 Sep;34(9):625-31. Epub 2007 Jun 29. Erratum in: J Ind Microbiol Biotechnol. 2007 Sep;34(9):633.

Industrial Biotechnology (PG)

Modern Research Techniques (UG)

Gene Therapy and Viral Vectors (UG)