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Dr. Muhammad Jawad Hassan
Assistant Professor
Healthcare Biotechnology

ASAB
National University of Sciences and Technology (NUST)
H-12 Sector, Islamabad, Pakistan 44000
Tel : +92 333 5690522

Specialization
Genetic mapping and characterization of genes involved in inherited neurological disorders in families belong to different ethnic/linguistic origins of Pakistan

Education
M. Phil., Ph. D., from Department of Biochemistry, Faculty of Biological Sciences, Quaid I Azam University, Islamabad, Pakistan.

Dr. M. Jawad Hassan got his MPhil and PhD from Department of Biochemistry, Quaid I Azam University Islamabad, Pakistan. He worked as Assistant Professor at Shifa College of Medicine-Shifa Tameer e Millat University, Islamabad (2011-2014) and Department of Biochemistry, University of Health Sciences, Lahore (2010-2011). Dr. Hassan worked as Director of PCR Laboratories at Shifa College of Medicine, Islamabad from 2013 to 2014. He has been a research associate in HEC funded project entitled “identification of hereditary deafness genes in Pakistan” from 2004 to 2005 at Quaid I Azam University, Islamabad. He joined ASAB, NUST as Assistant Professor Healthcare Biotechnology in 2014.
Dr. M. Jawad Hassan has got Research Productivity Award (RPA) in years 2007 and 2013 by Pakistan Council for Sciences & Technology (PCST), Ministry of Science & Technology, Pakistan.  He also won HEC indigenous PhD fellowship during his PhD at Quaid I Azam University, Islamabad.
Dr. Hassan was a member of editorial board of “The Ravi”, a historic literary journal of GCU, Lahore during his undergraduate studies. He won All Pakistan inter-board poetry competition in 1996 representing Sargodha board.
Dr. Hassan and his team are interested in identification of genes involved in inherited neurological disorders from Pakistan including pain insensitivity, ataxias, microcephaly syndromes, neurosensory deafness and muscular dystrophies. Dr. Hassan has supervised two MPhil students. Currently, one PhD fellow is working under his supervision. He has attained a cumulative impact factor of 75 and citations to his articles in peer reviewed journals are exceeding 180 (ISI web of knowledge, April, 2014).
Grants
HEC- Molecular Genetic Studies in Pakistani families with Schizophrenia-PI (2.9 Million PKR)
PSF- Molecular Genetic Studies in Pakistani families with Autosomal Recessive Primary Microcephaly (MCPH)-PI (1.1 Million PKR)
HEC- Studies on Protein Glycation and its effects in-vitro-Co-PI (0.5 Million PKR)   
 
1.    Abbas G, Hassan MJ, Saddiqe Z, Shahzad M, Hussain J, Perveen S, Maimoona A (2013) Non-Toxic Fractions of Hypericum perforatum and Hypericum oblongifolium Inhibit Protein Glycation, Free Radicals Production and Lipid Peroxidation in vitro. Int J Phytomedicine 5: (2), 191-196 (IF 0.89, Citations- 0)

2.    Abbas G, Shahzad M, Hassan MJ, Tareen RB, Choudhary MI (2012) Antiglycation, Antioxidant and Anti Lipid Peroxidation Activities of Microcephala lamelatta With Low Cytotoxic Effects In vitro.  MEJSR 11 (6): 814-818    (IF 0, citations-0)

3.    Mahmood S, Ahmad W, Hassan MJ (2011) Autosomal Recessive Primary Microcephaly: Autosomal Recessive Primary Microcephaly (MCPH): Clinical Manifestations, Genetic Heterogeneity, and Mutation Continuum. Orphanet Journal of Rare Diseases, 6: 39 (IF 4.315, citations-30)

4.    Qvist P, Huertas P, Jimeno S, Nyegaard M, Hassan MJ, Børglum AD, Jackson SP (2011) CtIP mutations cause Seckel and Jawad syndromes. PloS Genet, 7: 10-e 1002310 (IF 8.517, citations-13)

5.    Kousar R, Hassan MJ, Khan B, Basit S, Mahmood S, Mir A, Ahmad W, Ansar M (2011) Mutations in WDR62 gene in Pakistani families with autosomal recessive primary microcephaly. BMC Neurol 11- 119 (IF 2.564, citations-07)

6.    Wasif N, Tariq M, Ali G, Hassan MJ, Ahmad W (2010) A novel splice site mutation in the EDAR gene underlies autosomal recessive hypohidrotic ectodermal dysplasia in a Pakistani family. Pediatr Dermatol. 27: 106-108 (IF 1.041, citations-01)

7.    Schultz JM, Khan SN, Ahmed ZM, Riazuddin S, Waryah AM, Chhatre D, Starost MF, Ploplis B, Buckley S, Velásquez D, Kabra M, Lee K, Hassan MJ, Ali G, Ansar M, Ghosh M, Wilcox ER, Ahmad W, Merlino G, Leal SM, Riazuddin S, Friedman TB, Morell RJ (2009) Noncoding mutations of HGF are associated with nonsyndromic hearing loss, DFNB39. Am J Hum Genet 85: 25-39 (IF 11.202, citations-15)

8.    Azeem Z, Naqvi SK, Ansar M, Wali A, Naveed AK, Ali G, Hassan MJ, Tariq M, Basit S, Ahmad W (2009) Recurrent mutations in functionally-related EDA and EDAR genes underlie X-linked isolated hypodontia and autosomal recessive hypohidrotic ectodermal dysplasia. Arch Dermatol Res 301: 625-629 (IF 2.708, citations-04)

9.    Chishti MS, Lee K, McDonald ML, Hassan MJ, Ansar M, Ahmad W, Leal SM (2009) Novel autosomal recessive non-syndromic hearing impairment locus (DFNB71) maps to chromosome 8p22-21.3. J Hum Genet 54: 141-144 (IF 2.365, citations-02)

10.    Hassan MJ, Mahmood S, Ali G, Bibi N, Waheed I, Rafiq MA, Ansar M, Ahmad W (2008) Intragenic Deletions in the Dystrophin Gene in 211 Pakistani DMD Patients. Pediatr Int 50: 162-166 (IF 0.875, citations-05)

11. Bhatti A, Lee K, McDonald ML, Hassan MJ, Gutala R, Ansar M, Ahmad W, Leal SM (2008) Mapping of a new autosomal recessive non-syndromic hearing impairment locus (DFNB45) to chromosome 1q43-q44. Clin Genet 73: 395-398 (IF 4.242, citations-00)

12. Hassan MJ, Chishti MS, Jamal SM, Tariq M, Ahmad W (2008) A syndromic form of autosomal recessive congenital microcephaly (Jawad syndrome) maps to chromosome 18p11.22-q11.2. Hum Genet 123: 77-82 (IF 4.633, citations-07)

13. Gul A, Tariq M, Khan MN, Hassan MJ, Ali G, Ahmad W (2007) Novel protein-truncating mutations in the ASPM gene in families with autosomal recessive primary microcephaly. J Neurogenet 21: 153-163 (IF 2.159, citations-13)

14. Hassan MJ, Khurshid M, Azeem Z, John P, Ali G, Chishti MS, Ahmad W (2007) Previously described sequence variant in CDK5RAP2 gene in a Pakistani family with autosomal recessive primary microcephaly. BMC Med Genet 8:58-64 (IF 2.536, citations- 08)

15. Naeem M, Jelani M, Lee K, Ali G, Chishti MS, Wali A, Gul A, John P, Hassan MJ, Leal SM, Ahmad W (2006) Ectodermal dysplasia of hair and nail type: mapping of a novel locus to chromosome 17p12–q21.2. Brit J Dermatol 155: 1184-1190 (IF 3.759, citations-11)

16. Gul A, Hassan MJ, Hussain S, Raza SI, Chishti MS, Ahmad W (2006) A novel deletion mutation in CENPJ gene in a Pakistani family with autosomal recessive primary microcephaly. J Hum Genet 51:760–764 (IF 2.365, citations-23)

17. Wali A, John P, Gul A, Lee K, Chishti MS, Ali G, Hassan MJ, Leal SM, Ahmad W (2006) A novel locus for alopecia with mental retardation syndrome (APMR2) maps to chromosome 3q26.2-q26.31. Clin Genet 70: 233–239 (IF 4.242, citations-08)

18. Santose RLP, Hassan MJ, Sikandar S, Lee K, Ali G, Martin PE, Wambangco MAL, Ahmad W, Leal SM (2006) DFNB68, a novel autosomal recessive non-syndromic hearing impairment locus at chromosomal region 19p13.2. Hum Genet 120:85–92 (IF 4.633, citations-06)

19. Gul A, Hassan MJ, Mahmood S, Chen W, Rahmani S, Naseer MI, Dellafave L, Muhammad N, Rafiq MA, Ansar M, Chishti MS, Ali G, Siddique T, Ahmad W (2006) Genetic studies of autosomal recessive primary microcephaly in 33 Pakistani families: novel sequence variants in ASPM gene. Neurogenetics 7: 105–110 (IF 3.535, citations-23)

20. Tariq A, Santose RLP, Khan MN, Lee K, Hassan MJ, Ahmad W, Leal SM (2006) Localization of a novel autosomal recessive nonsyndromic hearing impairment locus DFNB65 to chromosome 20q13.2–q13.32. J Mol Med 84: 484–490 (IF 4.768, citations-01)

21. Hassan MJ, Santose RLP, Rafiq MA, Chahrour MH, Pham TL, Wajid M, Hijab N, Wambangco M, Lee K, Ansar M, Yan K, Ahmad W, Leal SM (2006) A novel autosomal recessive non-syndromic hearing impairment locus (DFNB47) maps to chromosome 2p25.1-p24.3. Hum Genet 118: 605–610 (IF 4.633, citations-5)
Dr. Hassan has teaching experience of four years to MBBS, MSc, MPhil & PhD students. Courses include Enzymology, Molecular Genetics, Molecular Biology, General Biochemistry, Medical Biochemistry. At ASAB, he is involved in teaching General Genetics (Bio 104) to Undergraduate students.