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Neurobiology LAB
​The Neurobiology Research laboratory seeks to unravel the mechanisms of cognitive functions, from attention and behavior to memory and executive control. We are interested in cognitive dysfunction in a broad spectrum of neurological, neurodevelopment and psychiatric disorders and aims to study various aspects of neuro-degeneration, using a multidisciplinary approach form behavioral studies to advanced molecular biology techniques.  
  
Group Members
Dr. Touqeer Ahmed (touqeer.ahmed@asab.nust.edu.pk)
Dr. Saadia Zahid (saadia.zahid@asab.nust.edu.pk)

Lab Equipments
Lab is fully equipped with the basic & specialized instruments to facilitate research including Two-Dimensional Gel Electrophoresis system, Semi dry Western blotting equipment (BioRad), Electro-enchephalography system, Fear conditioning test apparatus, Stereotaxic Surgical apparatus, Microtome, Spectrophotometer and Vertical gel electrophoresis system.

Grants & Awards
i. HEC Project: Elucidation of potential effects of anti-diabetics and acetylcholine esterase inhibitors: a comparative analysis for combined therapeutic strategies for type 2 diabetes and Alzheimer’s disease”.
ii. HEC Project: Elucidation of the effects of Amphetamine and natural psycho-stimulant compounds in Alzheimer’s disease”. 

Research Publications
i. Ozawa T, Ycu EA, Kumar A, Yeh LF, Ahmed T, Koivumaa J and Johansen JP. A feedback neural circuit for calibrating aversive memory strength. Nature Neuroscience. 2016. Nov 14.  doi:10.1038/nn.4439.
ii. Farhat SM, Mahboob A, Iqbal G, Ahmed T. Aluminum Induced Cholinergic Deficits in Different Brain Parts and Its Implications on Sociability and Cognitive Functions in Mouse. Biological Trace Element Research. 2016.
iii. Ahmed T, Zahid S, Mahboob A, Farhat SM. Cholinergic System and Post-translational Modifications: An Insight on the Role in Alzheimer’s disease. 2016, Curr Neuropharmacol. 
iv. Khalid A, Shakeel R, Justin S, Iqbal G, Shah SA, Zahid S, Ahmed T. Pharmacological effects of turmeric on learning, memory and expression of muscarinic receptor genes (M1, M3 and M5) in stress-induced mouse model. Curr Drug Targets. 2017. doi: 10.2174/1389450118666170315120627. 
v. Ahmed S, Mahmood Z, Javed A, Hashmi SN, Zerr I, Zafar S, Zahid S. Effect of Metformin on Adult Hippocampal Neurogenesis: Comparison with Donepezil and Links to Cognition. 2017. J Mol Neurosci. 62(1):88-98.
vi. Zahid S, Oellerich M, Asif AR, Ahmed N. Differential expression of proteins in brain regions of Alzheimer’s disease patients.  Neurochem Res. 2014. 39(1):208-15.